PharmDecks

Dermatology and Wound Management

Introduction: Guiding Healing Toward the Best Outcome

  • Effective wound care is grounded in knowledge of physiology, tailored to remove barriers, and designed to support optimal healing.

  • This lesson focuses on three pillars:

    • Moist wound healing

    • Debridement techniques

    • Dressing selection strategies


The Power of Moist Wound Healing

Modern evidence has revolutionised wound care: moist wounds heal faster, with fewer complications.

Benefits of Moist Wound Healing:

Benefit Explanation
🕒 Faster healing Moisture enhances cell migration (keratinocytes, fibroblasts) and promotes re-epithelialisation.
Less scarring Reduces inflammation and supports organized collagen deposition.
🛡️ Infection protection Prevents scab formation that can trap bacteria; many moist dressings contain antimicrobials.
🔬 Improved cell communication Growth factors and cytokines can function more effectively.
❤️ Enhanced angiogenesis Supports new blood vessel formation (critical for oxygen & nutrient delivery).
🔄 Autolytic debridement Encourages the body’s enzymes to remove dead tissue naturally.
😌 Less pain Moisture protects exposed nerve endings and reduces trauma during dressing changes.

Cleaning and Debridement: Preparing the Wound Bed

Wound healing can’t start effectively until non-viable tissue is removed.

What Is Debridement?

The process of removing:

  • Necrotic tissue

  • Scabs

  • Biofilm

  • Dried exudate

  • Infected tissue

 

💡 Goal: Convert a chronic wound into an acute healing wound by resetting the healing process.


Autolytic Debridement

  • Utilises body’s own enzymes and moisture.

  • Gentle, selective, and painless, but slow.

  • Best for stable wounds without infection.

Dressings:

  • Hydrogels

  • Hydrocolloids

  • Transparent films


Enzymatic Debridement

  • Uses topical enzymes to break down necrotic tissue.

Example:

  • Collagenase ointment

Slower than surgical, more selective than mechanical.


✂️ Surgical (Sharp) Debridement

  • Fast and effective, especially for infected or heavily necrotic wounds.

  • Done with scalpels, scissors, or curettes.

  • Requires clinical skill and consideration of pain and bleeding risk.

⚠️ Use caution in patients on anticoagulants or with bleeding disorders.


Dressing Selection: Strategic & Individualised

The right dressing supports the wound’s environment—moisture balance, infection control, protection, and comfort.


🧠 Considerations When Choosing a Dressing

Factor What to Assess
🧪 Wound bed Necrosis, slough, granulation tissue, epithelialisation
💧 Exudate level Dry, minimal, moderate, heavy
📍 Location Movement/friction, ease of application
👀 Periwound skin Maceration, irritation, eczema
🔥 Infection Use antimicrobial dressings if needed
👤 Patient needs Pain, allergies, ability to manage dressing, preferences
⏱️ Wear time How often it needs changing
📦 Dressing properties Absorbency, adherence, ease of removal

📋 Dressing Types & Indications

Dressing Type Best For
Film Superficial, low-exudate wounds; secondary dressing
Foam Moderate to high exudate; cushioning & absorption
Hydrogel Dry wounds; donate moisture; aid in debridement
Hydrocolloid Shallow, low-exudate wounds; supports autolysis
Alginate Heavy exudate; promotes granulation
Hydrofiber High exudate; reduces risk of maceration
Superabsorbent Very heavy exudate; high-capacity management
NPWT Complex wounds; promotes granulation & draws edges together

💬 Clinical Tip:

The dressing supports the wound—but doesn’t heal it alone. Addressing underlying causes (e.g., pressure, diabetes, infection) is essential.”


Reassessment Is Critical

  • Wounds evolve: reassess regularly.

  • Be ready to change dressing plans as:

    • Exudate level changes

    • Tissue status progresses

    • Infection emerges or resolves

    • Patient needs shift


Summary

Wound care is more than applying a bandage—it’s an evidence-based, patient-centred strategy that:

  • Optimises the healing environment 🌱

  • Promotes comfort and function 🧘

  • Prevents complications and scarring 🛡️


References

  1. Coloplast Professional. (n.d.). Understanding Moist Wound Healing. Retrieved from https://www.coloplastprofessional.co.uk/education-library/knowledge/advanced-wound-care-knowledge/wound-healing/understanding-moist-wound-healing/

  2. Sood, A., Granick, M. S., & Tomaselli, N. L. (2014). Wound dressings and comparative effectiveness data. Advances in Wound Care, 3(8), 511–529. Retrieved from https://pmc.ncbi.nlm.nih.gov/articles/PMC3842869/

  3. West Coast Wound Center. (n.d.). Benefits of Moist Wound Healing. Retrieved from https://westcoastwound.com/benefits-of-moist-wound-healing/

  4. Zhang, Y., Zhang, M., & Lin, W. (2021). Advances in biomaterials and dressings for wound healing. Frontiers in Bioengineering and Biotechnology, 9, 735616. Retrieved from https://pmc.ncbi.nlm.nih.gov/articles/PMC8568799/

  5. Velnar, T., Bailey, T., & Smrkolj, V. (2023). Wound healing and the role of the immune system. In StatPearls. StatPearls Publishing. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK507882/

  6. Pourmohammadi, K., et al. (2022). Emerging trends in wound healing strategies: Biomaterials and beyond. Journal of Translational Medicine, 20, 315. Retrieved from https://pmc.ncbi.nlm.nih.gov/articles/PMC9326937/

  7. WoundSource. (n.d.). Wound Debridement Options: 5 Major Methods. Retrieved from https://www.woundsource.com/blog/wound-debridement-options-5-major-methods

  8. Atkin, L. (2020). Wound assessment and dressing selection: An overview. British Journal of Nursing, 29(12), S4–S13. Retrieved from https://www.britishjournalofnursing.com/content/wound-assessment/wound-assessment-and-dressing-selection-an-overview/

  9. Elsayed, M. M. A., et al. (2023). Emerging wound healing approaches: A bibliometric and research trend analysis. Heliyon, 9(11), e18723. Retrieved from https://www.sciencedirect.com/science/article/pii/S2405844023036836

0% Complete