PharmDecks

Cardiovascular System

Introduction

  • Cardiovascular disease (CVD) is the leading cause of death globally, necessitating early identification and intervention.
  • Cardiac risk calculators estimate an individual’s risk of developing CVD, empowering proactive prevention strategies such as lifestyle changes and medication.

What is a Cardiac Risk Calculator?

  • A screening tool that evaluates the likelihood of future cardiovascular events based on individual risk factors.
  • Primarily for individuals without a prior heart attack, stroke, or heart failure.

Types of Cardiac Risk Calculators

  1. ASCVD Risk Calculator
    • Developed by the American College of Cardiology (ACC) and American Heart Association (AHA).
    • Estimates 10-year and lifetime risks of heart disease.
  2. Reynolds Risk Score
    • For individuals without diabetes.
    • Includes risk factors like age, sex, blood pressure, cholesterol, family history, and high-sensitivity C-reactive protein (hsCRP) levels.

Information Required for Cardiac Risk Assessment

  • Demographics: Age, sex, and race.
  • Medical History: Family history of premature heart disease (before age 60).
  • Lifestyle Factors: Smoking status.
  • Current Health Data:
    • Blood pressure.
    • Cholesterol levels.
    • Diabetes status.
    • Use of medications like statins, aspirin, or blood pressure medications.

Interpreting Cardiac Risk Scores

  • Calculators provide a percentage risk for developing CVD:
    • Low risk: < 5%.
    • Borderline risk: 5%–7.4%.
    • Intermediate risk: 7.5%–19.9%.
    • High risk: ≥ 20%.

Additional Tests for Comprehensive Risk Assessment

  • hsCRP Blood Test: Detects inflammation.
  • Lipid Panel: Evaluates cholesterol, including lipoprotein(a).
  • Electrocardiogram (ECG): Monitors heart’s electrical activity.
  • Exercise Stress Test: Assesses heart function during exertion.

Improving Heart Disease Risk Score

  1. Lifestyle Modifications:

    • Heart-Healthy Diet:
      • Limit: Saturated fats, trans fats, sodium, sugar, and red meat.
      • Increase: Fruits, vegetables, whole grains, lean protein (poultry, fish), and nuts.
    • Exercise: At least 150 minutes/week of moderate aerobic activity.
    • Weight Management: Achieve and maintain a healthy weight.
    • Stress Management: Adopt techniques like mindfulness and relaxation exercises.
    • Smoking Cessation: Stop smoking and avoid secondhand smoke.
  2. Medication Management:

    • Control conditions like hypertension, diabetes, and hypercholesterolemia through:
      • Adherence to prescribed medications (e.g., statins, blood pressure meds).
      • Regular monitoring and adjustments as needed.

The Role of Pharmacists in Cardiovascular Risk Management

Pharmacists are accessible healthcare professionals who play a significant role in risk reduction:

  1. Patient Education:

    • Provide information on CVD risk factors and importance of assessment.
    • Explain strategies for lifestyle and medication adherence.
  2. Medication Counselling:

    • Ensure understanding of prescribed medications, including statins and aspirin.
    • Address concerns about side effects and drug interactions.
  3. Lifestyle Support:

    • Encourage adoption of a heart-healthy diet and regular exercise.
    • Support smoking cessation efforts.
  4. Collaboration with Healthcare Teams:

    • Share insights with physicians and other healthcare providers.
    • Assist in optimising treatment plans based on risk scores and patient needs.

Conclusion

  • Cardiovascular risk calculators are essential tools for assessing and preventing CVD.
  • Pharmacists contribute by:
    • Educating patients.
    • Managing medications.
    • Supporting lifestyle modifications.
  • Active engagement in cardiovascular risk management improves outcomes and reduces the burden of CVD.

References

  1. Cleveland Clinic. Heart Risk Factor Calculators.
  2. Lam, C. S., & Pang, S. Y. Advances in cardiovascular risk prediction: The role of risk factor calculators.
  3. American College of Cardiology. Clinician Guide to the ABCs of Cardiovascular Risk Management.
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