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Cardiovascular & Endocrine Pathophysiology

Classifying Pain

  • Pain can be categorised by duration, damage type, tissue type, or the part of the body affected.
  • Syndromes: Some pain types are classified as syndromes, such as myofascial pain syndrome, which originates in muscle trigger points.

Duration of Pain

  • Acute Pain:
    • Sudden onset and temporary, lasting for a limited period.
    • Acts as a warning signal for potential harm, and treatment is individualised.
    • Example: A sprained ankle.
  • Chronic Pain:
    • Persists for 12 weeks or more and may resist medical treatment.
    • It is linked to long-term conditions and offers no benefit to the body.
    • Example: Arthritis or chronic headaches.
  • Breakthrough Pain:
    • Acute flare-ups that occur despite chronic pain management with medication.
    • Short-term episodes that “break through” ongoing pain relief.

Pain by Damage

  • Nociceptive Pain:
    • Triggered by the activation of pain receptors (nociceptors) due to harmful stimuli.

    • Can be acute or chronic.

    • Somatic Pain:

      • Originates from receptors on the body’s surface or musculoskeletal tissue.
      • Localised pain worsens with activity and improves with rest.
    • Visceral Pain:

      • Stems from receptors in internal organs.
      • Deep, pressure-like sensation, not well-localised.
  • Neuropathic Pain:
    • Results from damage to the nerves transmitting pain signals to the brain.

    • Often described as sharp, shooting pain, which tends to be more intense.

    • Examples of Neuropathic Pain:

      • Central Pain Syndrome: Chronic pain from central nervous system damage, worsened by movement or temperature changes.
      • Complex Regional Pain Syndrome: Post-injury chronic pain described as constant burning, often with swelling or colour changes.
      • Diabetic Peripheral Neuropathic Pain: Nerve damage from diabetes, commonly felt as burning or stabbing in the feet, hands, or legs.
      • Shingles and Postherpetic Neuralgia: Persistent pain following shingles, affecting a nerve pathway.
      • Trigeminal Neuralgia: Severe, lightning-like facial pain triggered by motion or touch.
  • Psychogenic Pain:
    • Linked to psychological conditions such as anxiety, depression, or stress, contributing to or worsening the pain.

Treatment of Pain

  • Pain management is typically handled in primary care, with treatment pathways provided by the British Pain Society.

Additional Notes

  • Pain Threshold vs. Pain Tolerance:
    • Pain threshold is the point at which a stimulus is perceived as painful.
    • Pain tolerance is the level of pain one can endure, which varies widely among individuals.
  • Mental Health:
    • Chronic pain can worsen mental health, leading to conditions like depression or anxiety, which, in turn, can intensify pain.
  • Breakthrough Pain:
    • Affects approximately 70% of individuals with chronic pain management, causing unexpected pain episodes.

This educational content aims to provide an overview of pain classifications and management. For diagnosis and treatment, always consult a healthcare professional.


References

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