Gastro-Intestinal System

The Gastro-Intestinal System module provides MPharm students with an integrated understanding of the anatomy, physiology, pathophysiology, and pharmacological management of gastrointestinal (GI) conditions. This module prepares students to confidently apply clinical knowledge in managing both acute and chronic GI disorders across a range of healthcare settings.

Beginning with the structure and function of the GI tract, students will explore digestion, absorption, gut motility, and the role of the enteric nervous system. The module then delves into common GI diseases including gastroesophageal reflux disease (GORD), peptic ulcer disease, inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), constipation, diarrhoea, coeliac disease, liver disease, and pancreatitis.

Pharmacological management is covered in detail, including the use of antacids, proton pump inhibitors, H2-receptor antagonists, antispasmodics, laxatives, antidiarrhoeals, aminosalicylates, immunosuppressants, and biologics. Students will also examine the pharmacokinetic implications of liver disease and the role of the pharmacist in managing GI-related drug interactions, adverse effects, and patient education.

The module incorporates UK clinical guidelines (e.g., NICE and BSG) to ensure alignment with current practice. Through clinical case studies, quizzes, and problem-based scenarios, students will develop the knowledge and decision-making skills required to manage complex GI presentations and optimise patient outcomes.